性能参数

产品名称

Procaine

规格

50mg

货号

GOY-Y3930

 含量

>98.00%

CAS

59-46-1

别名

化学名

2-(diethylamino)ethyl 4-aminobenzoate

分子式

C13H20N2O2

分子量

分子量 236.31

溶解度

≥ 8.7mg/mL in DMSO with gentle warming

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Procaine is a local anesthetic drug of the amino ester group, which acts through multiple targets.Target: OthersProcaine is a local anesthetic of the ester type that has a slow onset and a short duration of action.Procaine (0.01-100 microM) inhibited the 5-HT3 receptor-mediated inward current in the whole-cell patch clamp recording. Procaine appears to produce a competitive inhibition on 5-HT3 receptors with a KD of 1.7 microM [1]. Procaine is a DNA-demethylating agent that produces a 40% reduction in 5-methylcytosine DNA content as determined by high-performance capillary electrophoresis or total DNA enzyme digestion. Procaine can also demethylate densely hypermethylated CpG islands. Procaine also has growth-inhibitory effects in these cancer cells, causing mitotic arrest [2]. Procaine functions as an excitant of limbic system cells, and that procaine alters synaptic transmission in some, but not all, output pathways from the amygdale [3].

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