性能参数

产品名称

GSK9311

规格

10mM*1mLinDMSO2mg 5mg 10mg 25mg 50mg 100mg

货号

GOY-Y3902

 含量

>98.00%

CAS

1923851-49-3

别名

N/A

化学名

N/A

分子式

C24H31N5O3

分子量

分子量 437.53

溶解度

DMSO : ≥ 30 mg/mL (68.57 mM)

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

GSK9311 is a potent inhibitor of the BRPF bromodomain with pIC50 values of 6.0 and 4.3 for BRPF1 and BRPF2, respectively.

GSK6853 is a potent (300 pM), soluble, cell active (20 nM), and highly selective inhibitor of the BRPF1 bromodomain, and demonstrates properties suitable for cellular and in vivo studies. GSK6853 is a less active analogue of GSK6853 in which the 5-amide is alkylated[1].

[1]. Bamborough P, et al. GSK6853, a Chemical Probe for Inhibition of the BRPF1 Bromodomain. ACS Med Chem Lett. 2016 May 9;7(6):552-7.

3-羟基戊二酸二乙酯  32328-03-3  4-氟二苯基胺  330-83-6

2,6-二氯氟苯  134536  4-氯-3-硝基-5-磺酰胺基苯甲酸  22892-96-2

3,5-二硝基苯甲酸甲酯  2702-58-1  1-乙基-6-羟基-4-甲基-2-氧代-1,2-二氢-3-吡啶腈  28141-13-1

N-乙烯基己内酰胺  2235-00-9  甲氧基亚甲基马来酸二甲酯  22398-14-7

2-噻吩甲酰肼  2361-27-5  衣康酸二乙酯(含稳定剂叔丁基邻苯二酚)  2409-5

叠氮化钠Sodium azide,≥99.5%26628-22-850G

戊四氮Pentylenetetrazole (≥99.0%)54-95-51G

乙醇氧化酶Alcohol Oxidase9073-63-6250U

乙酰辅酶A三锂盐Acetyl CoA trilithium salt,≥93%75520-41-11MG

2,4-二甲基吡咯2,4-Dimethyl-1H-pyrrole,97%625-82-11G

草酸酰胺乙酯Ethyl oxamate,98%617-36-725G