性能参数

产品名称

Ro 41-0960

规格

5mg  10mg 25mg

货号

GOY-Y3628

 含量

>98.00%

CAS

125628-97-9

别名

N/A

化学名

N/A

分子式

C13H8FNO5

分子量

分子量 277.2

溶解度

DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml,PBS (pH 7.2): 0.2 mg/ml

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Ro 41-0960 is a catechol-O-methyltransferase (COMT) inhibitor.1 It prevents dopaminergic neuron loss induced by L-DOPA in primary rat rostral mesencephalic tegmentum cultures (EC50 = 0.1 μM). Ro 41-0960 (30 mg/kg) potentiates L-DOPA and carbidopa-induced reversal of reserpine-induced akinesias in rats and reserpine-induced catalepsy and hypothermia in mice.2 It reduces striatal 3-methyl-DOPA levels and increases striatal dopamine and 3,4-dihydroxyphenylacetic acid levels in rats. Ro 41-0960 (150 mg/kg) also reduces fibroid volume in the Eker rat model of uterine fibroids.3

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4-溴乙基四氢吡喃  4677-20-7  7-氯-4-羟基喹啉-3-羧酸  86-47-5

7-氯-1,4-二氢-4-氧代-3-喹啉羧酸乙酯  16600-22-9  7-溴-4-羟基喹啉-3-甲酸  82121-06-0

7-溴-4-羟基-3-喹啉羧酸  860205-92-1  7-溴-4-羟基喹啉-3-甲酸乙酯

2,6-吡啶二甲醛2,6-Pyridinedicarboxaldehyde,97%5431-44-7500MG

2-甲基吲哚-3-甲醛2-Methylindole-3-carboxaldehyde,97%5416-80-85G

3-叔丁基苯酚3-tert-Butylphenol,99%585-34-25G

吡咯-2-甲醛Pyrrole-2-carboxaldehyde,98%1003-29-85G

5-羟基-2-硝基苯甲醛5-Hydroxy-2-nitrobenzaldehyde,98%42454-06-81G

4-溴苯甲醛二乙基缩醛4-Bromobenzaldehyde diethyl acetal,99%34421-94-85G