性能参数

产品名称

Resminostat 

规格

5mg  10mg 50mg

货号

GOY-Y3624

 含量

>98.00%

CAS

864814-88-0

别名

N/A

化学名

(E)-3-[1-[4-[(dimethylamino)methyl]phenyl]sulfonylpyrrol-3-yl]-N-hydroxyprop-2-enamide

分子式

C16H19N3O4S

分子量

分子量 349.4

溶解度

Soluble in DMSO

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Resminostat, also known as RAS2410, is a potent inhibitor of histone deacetylase (HDAC) classes I and II (including HDAC1, HDAC3 and HDAC6) with 50% inhibition concentration IC50 values ranging from 43 to 72 nmol/L. Resminostate has the potential to be used for the treatment of multiple myeloma (MM) due to its ability to induce histone H4 hyperacetylation, and apoptosis (IC50 ranging from 2.5 to 3 μmol/L) in MM cells. Recent study results have shown that, in MM cell lines, resminostat abrogates cell growth, suppresses proliferation and induce G0/G1 cell cycle arrest as well as interfering with Akt signaling pathway by decreasing phosphorylation of 4E-BP1 and p70S6k.

7-羟基-6-甲氧基-3,4-二氢异喹啉  4602-73-7  6-甲氧基异喹啉  52986-70-6

6-甲氧基-异吲哚啉-1-酮  132680-54-7  6-喹啉羧酸甲酯  38896-30-9

6-喹啉甲酸乙酯  73987-38-9  6-氯-1,2,3,4-四氢异喹啉  33537-99-4

6-氯-1,2,3,4-四氢异喹啉盐酸盐  33537-97-2  6-氯-2-甲酰胺基吡啶  70593-61-2

5-氯靛红酸酐  4743-17-3  5-氯喹啉  635-27-8

5-氯异

N-乙烯基吡咯烷酮1-Vinyl-2-pyrrolidinone,≥99%88-12-0100ML

聚乳酸Polylactic acid,Mw ~60,00026100-51-61G

3-甲氧基-4-羟基苯...4′-Hydroxy-3′-methoxyacetophenone,98%498-02-225G

乙二胺四乙酸三钠EDTA,3Na,≥98.0%150-38-925G

甲硫醇钠盐Sodium thiomethoxide,95%12011081G

3-乙酰脱氧瓜萎镰醇3-Acetyldeoxynivalenol,98%50722-38-81MG