性能参数

产品名称

Gambogenic acid

规格

1mg  5mg 10mg

货号

GOY-Y3574

 含量

>98.00%

CAS

173932-75-7

别名

N/A

化学名

N/A

分子式

C38H46O8

分子量

分子量 630.77

溶解度

DMSO: 250 mg/mL (396.34 mM)

储存条件

4°C, protect from light

General tips

用途

仅供科研

价格

电询

详细内容

Gambogenic acid is an active ingredient in gamboge, with anticancer activity. Gambogenic acid acts as an effective inhibitor of EZH2, specifically and covalently binds to Cys668 within the EZH2-SET domain, and induces EZH2 ubiquitination[1].

[1]. Wang X, et al. A covalently bound inhibitor triggers EZH2 degradation through CHIP-mediated ubiquitination. EMBO J. 2017 May 2;36(9):1243-1260.

1-氯-4-氟苯  352-33-0  对氟碘苯  352-34-1

2-吡嗪基乙硫醇  35250-53-4  4-乙炔基吡啶盐酸盐  352530-29-1

4-三氟甲氧基氟苯  352-67-0  D-氨基丙醇  35320-23-1

DL-2-硝基苯丙氨酸  35378-63-3  2-甲基丙烷磺酰氯  35432-36-1

2,2,2-三氟乙酰胺  354-38-1  对氨基苯乙腈  3544-25-0

5-溴烟腈  35590-37-5  N-芴甲氧羰基-L-丙氨酸  35661-39-3

异戊醚Isoamyl ether,99%544-01-425ML

二乙硫醚Diethyl sulfide,98%352-93-225ML

对硝基苯甲醚4-Nitroanisole,98%100-17-425G

异丁基乙烯基醚Isobutyl vinyl ether,99%109-53-5100ML

丙二醇甲醚1-Methoxy-2-propanol,≥99.0%107-98-2250ML

乙基叔丁基醚tert-Butyl ethyl ether,99%637-92-310G