性能参数

产品名称

BRCA1-IN-2

规格

100mg  250mg 500mg

货号

GOY-Y3554

 含量

>98.00%

CAS

1622262-55-8

别名

N/A

化学名

N/A

分子式

C26H33N4O7P

分子量

分子量 544.54

溶解度

Soluble in DMSO

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

BRCA1-IN-2 (compound 15) is a cell-permeable protein-protein interaction (PPI) inhibitor for BRCA1 with an IC50 of 0.31 μM and a Kd of 0.3 μM, which shows antitumor activities via the disruption of BRCA1 (BRCT)2/protein interactions[1]. IC50: 0.31 μM (BRCA1)[1]Kd: 0.3 μM (BRCA1)[1]

[1]. Na Z, et al. Protein-Protein Interaction Inhibitors of BRCA1 Discovered Using Small Molecule Microarrays. Methods Mol Biol. 2017;1518:139-156.

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