L Moses dihydrochloride
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产品名称:
L Moses dihydrochloride
产品型号:
GOY-Y3514
产品展商:
谷研
产品文档:
无相关文档
发布时间:2023-05-08
简单介绍
L Moses dihydrochlorideSoluble in DMSO
L Moses dihydrochloride
的详细介绍
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性能参数
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产品名称
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L Moses dihydrochloride
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规格
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mg 50 mg
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货号
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GOY-Y3514
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含量
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>98.00%
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CAS
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N/A
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别名
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N/A
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化学名
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N/A
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分子式
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C21H24N6.2HCl
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分子量
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分子量 433.38
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溶解度
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Soluble in DMSO
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储存条件
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Store at -20°C
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General tips
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用途
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仅供科研
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价格
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电询
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详细内容
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High affinity and selective cell-permeable p300/CBP-associated factor (PCAF) inhibitor (Ki = 47 nM). Exhibits no significant activity against a panel of 48 other bromodomains except GCN5 (Kd = 600 nM). Exhibits >4500-fold selectivity for PCAF over BRD4. Also exhibits metabolic stability in mouse and human liver microsomes and no observable cytotoxicity in peripheral blood mononuclear cells (PBMC).
Moustakim et al (2017) Discovery of a PCAF bromodomain chemical probe. Angew.Chem.Int.Ed. 56 827 PMID:27966810
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