性能参数

产品名称

Moracin O

规格

5 mg

货号

GOY-Y3446

 含量

>98.00%

CAS

123702-97-6

别名

N/A

化学名

N/A

分子式

C19H18O5

分子量

分子量 326.34

溶解度

N/A

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Moracin O is a 2-arylbenzofuran isolated from the Mori Cortex Radicis. Moracin O exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1). Moracin O reduces oxygen-glucose deprivation (OGD)-induced reactive oxygen species (ROS) production. Moracin O has neuroprotective and anti-inflammatory effects[1][2][3].

Moracin O enhances cell viability in dose-dependent manner against oxygen-glucose deprivation (OGD)-induced cell death in neuroblastoma SH-SY5Y cells with an EC50 value of 12.6 μM. Moracin O reduces ROS production in OGD-induced cell death (IC50 value of 0.3 μM). Moracin O protects neuronal cell death against the oxidative stress induced by OGD[1].

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