性能参数

产品名称

5-Fluoro-2'-deoxycytidine

规格

5 mg

货号

GOY-Y3425

 含量

>98.00%

CAS

10356-76-0

别名

N/A

化学名

N/A

分子式

C9H12FN3O4

分子量

分子量 245.21

溶解度

N/A

储存条件

4°C, protect from light

General tips

用途

仅供科研

价格

电询

详细内容

5-Fluoro-2'-deoxycytidine, a fluoropyrimidine nucleoside analogue, is a DNA methyltransferase (DNMT) inhibitor. 5-Fluoro-2'-deoxycytidine is a tumor-selective prodrug of the potent thymidylate synthase inhibitor 5-fluoro-2′-dUMP[1][2].

[1]. Beumer JH, et, al. Pharmacokinetics, metabolism, and oral bioavailability of the DNA methyltransferase inhibitor 5-fluoro-2'-deoxycytidine in mice. Clin Cancer Res. 2006 Dec 15;12(24):7483-91. [2]. Osterman DG, et, al. 5-Fluorocytosine in DNA is a mechanism-based inhibitor of HhaI methylase. Biochemistry. 1988 Jul 12;27(14):5204-10.

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