性能参数

产品名称

Sesquicillin A

规格

1 mg

货号

GOY-Y3405

 含量

>70.00%

CAS

51103-58-3

别名

N/A

化学名

N/A

分子式

C29H42O5

分子量

分子量 470.6

溶解度

Dichloromethane: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Sesquicillin A is a fungal metabolite that has been found in Albophoma.1 It inhibits the growth of A. salina brine shrimp (MIC = 6.25 μg/ml). Sesquicillin is cytotoxic to Jurkat cells (IC50 = 34 μM). It induces cell cycle arrest at the G1 phase and inhibits proliferation of MCF-7 breast cancer cells when used at a concentration of 20 μg/ml.2

1.Uchida, R., Imasato, R., Yamaguchi, Y., et al.New sesquicillins, insecticidal antibiotics produced by Albophoma sp. FKI-1778J. Antibiot. (Tokyo)58(6)397-404(2005) 2.Jeong, H.W., Lee, H.J., Kho, Y.H., et al.Biological effects of G1 phase arrest compound, sesquicillin, in human breast cancer cell linesBioorg. Med. Chem.10(10)3129-3134(2002)

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