性能参数

产品名称

Nocardamine

规格

1 mg

货号

GOY-Y3403

 含量

>70.00%

CAS

26605-16-3

别名

N/A

化学名

N/A

分子式

C27H48N6O9

分子量

分子量 600.7

溶解度

Dichloromethane: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Nocardamine is a ferrioxamine siderophore that has been found in Streptomyces and has diverse biological activities.1,2,3,4 It chelates iron in a chrome azurol S assay (IC50 = 9.9 μM).1 Nocardamine inhibits M. smegmatis and M. bovis biofilm formation (MIC = 10 μM for both), an effect that can be reversed by iron.2 It is cytotoxic to T47D, SK-MEL-5, SK-MEL-28, and RPMI-7951 cancer cells (IC50s = 6, 18, 12, and 14 μM, respectively).3 Nocardamine also induces morphological changes in BM-N4 insect cells.4

1.Lopez, J.A.V., Nogawa, T., Futamura, Y., et al.Nocardamin glucuronide, a new member of the ferrioxamine siderophores isolated from the ascamycin-producing strain Streptomyces sp. 80H647J. Antibiot. (Tokyo)72(12)991-995(2019) 2.Ishida, S., Arai, M., Niikawa, H., et al.Inhibitory effect of cyclic trihydroxamate siderophore, desferrioxamine E, on the biofilm formation of Mycobacterium speciesBiol. Pharm. Bull.34(6)917-920(2011) 3.Kalinovskaya, N.I., Romaneko, L.A., Irisawa, T., et al.Marine isolate Citricoccus sp. KMM 3890 as a source of a cyclic siderophore nocardamine with antitumor activityMicrobiol. Res.166(8)654-661(2011) 4.Matsubara, K., Sakuda, S., Tanaka, M., et al.Morphological changes in insect BM-N4 cells induced by nocardamineBiosci. Biotechnol. Biochem.62(10)2049-2051(1998)

1-氨基-3,5-二甲苯  108-69-0  1,3,5-三氯苯  108-70-3

间苯三酚  108-73-6  苯硫酚  108-98-5

2-甲基哌嗪  109-07-9  3-吗啉酮  109-11-5

N-叔丁氧羰基-(R)-3-吡咯烷醇  109431-87-0  3-氯-1-(N,N-二甲基)丙胺  109-54-6

异丙氧基乙醇  109-59-1  乙酸丙酯  109-60-4

正丁基锂  109-72-8  烯丙基腈  109-75-1

BPK-2510mM*1 mL in DMSO 5 mg 10 mg 25 mg 50 mg>99.50%Cas No. 2305052-86-0C21H17ClN4O2

IMD-05601mg 5mg 10mg 50mg 100mg>99.50%Cas No. 439144-66-8C15H8BrF6NO2

MD2-IN-11mg 5mg 10mg 25mg 50mg>99.50%Cas No. 111797-22-9C20H22O6

ML RR-S2 CDA (ammonium salt)1mg 5mg 10mg 25mg 50mg>99.50%Cas No. 1638750-96-5C20H22N10O10P2S2.2NH4

NDMC1015 mg 10 mg 25 mg 50 mg 100 mg>99.50%Cas No. 1308631-40-4C13H9ClFNO2

14-deoxy-11,12-didehydro Andrographolide500μg 1mg 5mg 10mg>99.50%Cas No. 42895-58-9C20H28O4