性能参数

产品名称

Risuteganib (trifluoroacetate salt)

规格

1mg 5mg 10mg

货号

GOY-Y3384

 含量

>95.00%

CAS

N/A

别名

N/A

化学名

N/A

分子式

C22H39N9O11S?XCF3COOH

分子量

分子量 637.7

溶解度

DMSO: soluble

储存条件

-20°C

General tips

用途

仅供科研

价格

电询

详细内容

Risuteganib is an anti-integrin peptide and a derivative of RGD peptide .1 Risuteganib (400 μM) protects against hydroquinone-induced necrosis and apoptosis, as well as inhibits hydroquinone-induced production of reactive oxygen species (ROS), in human retinal pigment epithelial (RPE) cells.2 It decreases the expression of BAX, VEGFA, and ITB1 in human age-related macular degeneration (AMD) cybrid cell lines when used at a concentration of 20 mg/ml.3 Risuteganib arrests aberrant blood vessel growth mediated by αVβ3, αVβ5, and α5β1 integrins in vivo.1

1.Kaiser, P., Boyer, D.D., Campochiaro, P.A., et al.Integrin peptide therapy: The first wet AMD experienceInvest. Opth. Vis. Sci.54(15)2177(2013) 2.Yang, P., Shao, Z., Besley, N.A., et al.Risuteganib protects against hydroquinone-induced injury in human RPE cellsInvest. Ophthalmol. Vis. Sci.61(10)35(2020) 3.Differential effects of risuteganib and bevacizumab on AMD cybrid cellsExp. Eye Res.203108287(2021)

3-氯-2-甲基苯甲酸  2045209  碘乙烷  27459

氯化钯  2099324  乙酸  29167

N-甲基-N-亚硝基对甲苯磺酰胺  29530  糖精  29769

菲  31055  N,N-二乙基氯甲酰胺  32424

阿拉伯树胶  2593228  1-溴化萘  33186

对羟基联苯  92-69-3  3,4-二甲氧基苯甲酸  34152

1,4-Chrysenequinone (Chrysene-1,4-dione)10mM*1mLinDMSO 50mg>98.00%Cas No. 100900-16-1C18H10O2

17(R)-Protectin D110 μg 25 μg>98.00%Cas No. 1365694-03-6C22H32O4

2-TEDC10mg 50mg>98.00%Cas No. 132465-10-2C16H13NO4S

2-Iminopiperidine hydrochloride10mg 50mg>98.00%Cas No. 16011-96-4C5H10N2.HCl

2-Iminobiotin50mg 100mg>98.00%Cas No. 13395-35-2C10H17N3O2S

2,4-Dichlorobenzenesulfonyl chloride1 g 5 g>98.00%Cas No. 16271-33-3C6H3Cl3O2S

2'3'-cGAMP (sodium salt)500μg 1mg>98.00%Cas No. N/AC20H22N10O13P2?2Na