性能参数

产品名称

Resveratrol-3-O-Sulfate (sodium salt)

规格

500μg 1mg

货号

GOY-Y3366

 含量

>95.00%

CAS

858127-11-4

别名

N/A

化学名

N/A

分子式

C14H11O6S?Na

分子量

分子量 330.3

溶解度

DMSO: Slightly Soluble

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Resveratrol-3-O-sulfate is a metabolite of resveratrol . In U-937 cells stimulated with LPS, resveratrol-3-O-sulfate (1 μM) decreases the expression of IL-1α, IL-1β, and IL-6 by 61.2, 76.6, and 42.2%, respectively, and decreases the release of TNF-α and IL-6 to similar levels as resveratrol. It has antioxidant activity in a Trolox assay, dose-dependently decreases growth of Caco-2 colorectal adenocarcinoma cells when used at concentrations ranging from 10 to 100 μM, and induces apoptosis at concentrations of 25 and 50 μM. Resveratrol-3-O-sulfate also displaces rosiglitazone from the outer mitochondrial protein mitoNEET (IC50 = 3.36 μM for the human protein), indicating that it binds to the thiazolidine-2,4-dione (TZD) binding pocket.

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