性能参数

产品名称

Siomycin A

规格

500μg

货号

GOY-Y3348

 含量

>95.00%

CAS

12656-09-6

别名

N/A

化学名

N/A

分子式

C71H81N19O18S5

分子量

分子量 1648.9

溶解度

DMF: Soluble,DMSO: Soluble

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

The mammalian transcription factor forkhead box M1 (FoxM1) is induced during G1 phase, with expression continuing through S phase and mitosis. Siomycin A is a peptide thiazole antibiotic, first isolated from S. sioyaensis, that interacts with the 23S rRNA of bacteria. It inhibits FoxM1 (IC50 = ~5 μM), preventing the expression of FoxM1-regulated genes, which includes FoxM1 itself. Through this mechanism, siomycin A prevents proliferation and induces apoptosis in certain types of stem cells as well as cancer cells.

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4-氟?

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Purity: >95.00%