PROTAC RIPK degrader-6
如果您对该产品感兴趣的话,可以
产品名称:
PROTAC RIPK degrader-6
产品型号:
GOY-Y3325
产品展商:
谷研
产品文档:
无相关文档
发布时间:2023-05-05
简单介绍
PROTAC RIPK degrader-6DMSO: 100 mg/mL (112.49 mM)
PROTAC RIPK degrader-6
的详细介绍
|
性能参数
|
|
产品名称
|
PROTAC RIPK degrader-6
|
|
规格
|
10mM*1 mL in DMSO 5mg 10mg 25mg
|
|
货号
|
GOY-Y3325
|
|
含量
|
>99.00%
|
|
CAS
|
2089205-64-9
|
|
别名
|
N/A
|
|
|
|
化学名
|
N/A
|
分子式
|
C43H48N6O11S2
|
|
分子量
|
分子量 889
|
溶解度
|
DMSO: 100 mg/mL (112.49 mM)
|
|
储存条件
|
Store at -20°C
|
General tips
|
|
|
用途
|
仅供科研
|
价格
|
电询
|
|
|
|
详细内容
|
PROTAC RIPK degrader-6 (example 1) is a PROTAC targeting RIP Kinase degradation wherein the RIP2 kinase inhibitor is linked via a linker to a cereblon binder[1].
PROTACs is useful for the targeted degradation of proteins and other polypeptides which on the one end binds to the cereblon and on the other end to the target protein (RIP2 kinase). By bringing the target protein in close proximity to the E3-Ligase, these compounds form a ternary complex leading to polyubiquitination of the target protein inducing its degradation[1].
[1]. John David Harlin, et al. Compounds for the modulation of rip2 kinase activity. WO2017046036A1
|
公司正在销售的产品：
|
4-甲基氨基硫脲 6610-29-3 3,5-二甲基苯甲酰氯 6613-44-1
4-溴甲基苯磺酰氯 66176-39-4 异喹啉-3-甲酸 6624-49-3
4-溴间苯二酚 6626-15-9 3-氯-4-溴甲苯 6627-51-6
2-溴-4-甲基苯酚 6627-55-0 5-氨基-2-甲氧基吡啶 6628-77-9
5-硝基香兰素 6635-20-7 盐酸雷尼替丁 66357-59-3
2-甲氧基-4-甲基-5-硝基吡啶 6635-90-1 6-氯-2-吡啶羧酸甲?
|
SB 399885 hydrochloride10mg 50mg>99.50%Cas No. 402713-81-9C18H21Cl2N3O4S.HCl
SB 24208410mg 50mg>99.50%Cas No. 181632-25-7C21H19ClN4O2
Salsolinol-1-carboxylic acid10mg 50mg>99.50%Cas No. 57256-34-5C11H13NO4
Serotonin HCl10mM (in 1mL DMSO) 50mg>99.50%Cas No. 153-98-0C10H12N2O.HCl
SNAP 94847 hydrochloride10mg 50mg>99.50%Cas No. 487051-12-7C29H32F2N2O2.HCl
Tenoxicam10mM (in 1mL DMSO) 50mg>99.50%Cas No. 59804-37-4C13H11N3O4S2
Tegaserod maleate10mg 50mg>99.50%Cas No. 189188-57-6C16H23N5O.C4H4O4
|