性能参数

产品名称

Pomalidomide

规格

10mM (in 1mL DMSO) 10mg 50mg 200mg

货号

GOY-Y3324

 含量

>99.00%

CAS

19171-19-8

别名

Actimid,4-Aminothalidomide,CC 4047

化学名

4-amino-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione

分子式

C13H11N3O4

分子量

分子量 273.2

溶解度

≥ 7.5 mg/mL in DMSO

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Pomalidomide, previously known as CC-4047 or actimid, is a potent immunomodulatory molecule that exhibits antineoplastic activity for the treatment of hematological malignancies, especially relapsed and refractory multiple myeloma (MM). As a derivative of thalidomide, pomalidomide has a similar chemical structure as thalidomide except for the addition of two oxo groups in the phthaloyl ring and an amino group at the fourth position. Generally, as an immunomodulatory molecule, pomalidomide demonstrates antitumor activity through a mechanism of blocking the tumor microenvironment by modulation of tumor-supporting cytokines (TNF-α, IL-6, IL-8 and VEGF), directly down-regulating key functions of tumor cells, and engaging support from non-immune host cells.

2-双环己基膦-2',6'-二甲氧基联苯  657408-07-6  2,3-二氯苯腈  6574-97-6

3,4-二氯苯腈  6574-99-8  3,5-二氯苯腈  6575-00-4

3,4-二氟酸  658-93-5  2-溴-6-氟苯胺  65896-11-9

3,4-二氟苯乙腈  658-99-1  虎杖甙  65914-17-2

2-甲基-5-吡啶硼酸  659742-21-9  安石榴苷  65995-63-3

L-正缬氨酸  6600-40-4  2-氯-3-氰基吡啶  6602-?

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