性能参数

产品名称

Triclabendazole-13C-d3

规格

500 μg 1 mg 5 mg

货号

GOY-Y3316

 含量

>99.00%

CAS

N/A

别名

N/A

化学名

N/A

分子式

C13[13C]H6D3Cl3N2OS

分子量

分子量 363.7

溶解度

Acetonitrile: soluble,DMSO: soluble,Methanol: soluble

储存条件

-20°C

General tips

用途

仅供科研

价格

电询

详细内容

Triclabendazole-13C-d3 is intended for use as an internal standard for the quantification of triclabendazole by GC- or LC-MS. Triclabendazole is a benzimidazole anthelmintic.1 It eliminates both immature and  flukes in a sheep model of F. hepatica infection when administered at a dose of 10 mg/kg.2 Triclabendazole (5 μM) also protects against glucose- or α-synuclein-induced apoptosis in S. cerevisiae via inhibition of adenylyl cyclase in the Ras-adenylyl cyclase-protein kinase A (PKA) nutrient sensing pathway.3

1.Shrifi, Y., Farahnak, A., Golestani, A., et al.Triclabendazole effect on protease enzyme activity in the excretory- secretory products of Fasciola hepatica in vitroIran. J. Parasitol.9(1)107-113(2014) 2.Smeal, M.G., and Hall, C.A.The activity of triclabendazole against immature and  Fasciola hepatica infections in sheepAust. Vet. J.60(11)329-331(1983) 3.Lee, Y.J., Burlet, E., Wang, S., et al.Triclabendazole protects yeast and mammalian cells from oxidative stress: Identification of a potential neuroprotective compoundBiochem. Biophys. Res. Commun.414(1)205-208(2011)

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