性能参数

产品名称

Meloxicam-d3

规格

500μg 1mg

货号

GOY-Y3295

 含量

>99.00%

CAS

942047-63-4

别名

N/A

化学名

N/A

分子式

C14H10D3N3O4S2

分子量

分子量 354.4

溶解度

DMF: 20 mg/ml,DMSO: 20 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Meloxicam-d3 is intended for use as an internal standard for the quantification of meloxicam by GC- or LC-MS. Meloxicam is a selective inhibitor of COX-2 (IC50s = 11.8 and 143 μM for COX-2 and COX-1, respectively, in an enzyme activity assay) and a non-steroidal anti-inflammatory drug (NSAID). Meloxicam (0.03%) reduces croton oil-induced increases in TNF-α and IL-1β mRNA levels and increases IL-10 mRNA levels in cornea in a rabbit model of acute ocular inflammation. It inhibits pleural plasma exudation in a carrageenan-induced rat model of pleurisy when administered at a dose of 3 mg/kg. In a canine model of unilateral osteoarthritis of the right stifle joint, meloxicam reduces prostaglandin E2 (PGE2) levels in plasma and right stifle joint synovial fluid when administered at a dose of 0.2 mg/kg. Formulations containing meloxicam have been used in the treatment of osteoarthritis and rheumatoid arthritis.

4-氯-2-氟苯腈  57381-51-8    57-44-3

1-苄基吡咯烷-3-羧酸乙酯  5747-92-2  2-甲硫基-4-嘧啶酮  5751-20-2

硝酸铽  57584-27-7  2,6-二甲基溴苯  576-22-7

2,3-二甲基溴苯  576-23-8  2,3-二氯苯酚  576-24-9

5-甲基异恶唑  5765-44-6  5-巯基-1H-四氮唑-1-乙酸  57658-36-3

2-溴-1,3,5-**基苯  576-83-0  多库脂钠  577-11-7

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