Pitavastatin Calcium
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产品名称:
Pitavastatin Calcium
产品型号:
GOY-Y3194
产品展商:
谷研
产品文档:
无相关文档
发布时间:2023-05-05
简单介绍
Pitavastatin Calcium≥ 34.85mg/mL in DMSO
Pitavastatin Calcium
的详细介绍
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性能参数
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产品名称
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Pitavastatin Calcium
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规格
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10mM (in 1mL DMSO) 10mg 25mg
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货号
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GOY-Y3194
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含量
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>98.00%
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CAS
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147526-32-7
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别名
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化学名
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calcium;(E,3R,5S)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoate
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分子式
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C50H46CaF2N2O8
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分子量
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分子量 880.98
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溶解度
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≥ 34.85mg/mL in DMSO
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储存条件
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4°C, protect from light
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General tips
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用途
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仅供科研
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价格
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电询
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详细内容
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Pitavastatin Calcium is a competitive inhibitor of the enzyme HMGCR (HMG-CoA reductase) results in a reduction in LDL cholesterol synthesis. Alternate studies show that pitavastatin can suppress oxygen production in endothelial cells by inhibiting NADPH oxidase. In addition, pitavastatin reduces the expression of eNOS mRNA while increasing the NO dependent response stimulated by acetylcholine and the calcium ionophore, A23187. Furthermore, pitavastatin inhibits the up-regulation of conductance calcium-activated potassium channels by lowering cholesterol levels in cells.
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