性能参数

产品名称

Mitotane (Lsodren)

规格

10mM (in 1mL DMSO) Mitotane(Lsodren) 100mg Mitotane(Lsodren) 500mg

货号

GOY-Y3180

 含量

>98.00%

CAS

53-19-0

别名

化学名

1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]benzene

分子式

C14H10Cl4

分子量

分子量 320.04

溶解度

≥ 12.5mg/mL in DMSO

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Mitotane(2,4′-DDD), an isomer of DDD and derivative of DDT, is an antineoplastic medication used in the treatment of adrenocortical carcinoma.IC50 value: Target: Mitotane alters steroid peripheral metabolism, directly suppresses the adrenal cortex and alters cortisone metabolism leading to hypocortisolism. Side effects as reported by Schteinberg et al. include anorexia and nausea (88%), diarrhea (38%), vomiting (23%), decreased memory and ability to concentrate (50%), rash (23%), gynecomastia (50%), arthralgia (19%), and leukopenia (7%).

四氟硼酸锂  14283-07-9   N-Boc-4-哌甲酸乙酯  142851-03-4

二丁醚  142-96-1  5-甲基苯并噻吩  14315-14-1

溴代十二烷  143-15-7  2-脱氧-2,2-二氟-3,5-二苯甲?；?D-呋喃核糖  143157-22-6

D-丙氨酸甲酯盐酸盐  14316-06-4  四乙二醇二甲醚  143-24-8

十六胺  143-27-1  L-环己基甘氨酸  14328-51-9

3,4,5-三氟苯硼酸  143418-49-9  (R)-(-)-?

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