性能参数

产品名称

Lomustine

规格

10mM (in 1mL DMSO) 250mg 500mg

货号

GOY-Y3173

 含量

>98.00%

CAS

13010-47-4

别名

化学名

1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea

分子式

C9H16ClN3O2

分子量

分子量 233.7

溶解度

≥ 11.7mg/mL in DMSO

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Lomustine is an antineoplastic drug used in chemotherapy [1]

Lomustine has been revealed to inhibit the growth of tumour cell lines with IC50 values of 25μM, 8.8μM and 13μM for breast ZR-75-1, astrocytoma U87MG and colorectal LS174T cell lines [2]. Besides, Lomustine has been found to be particularly effective in the treatment of certain neoplasms of the central nervous system, because of the high lipid solubility and permeability through the blood brain barrier. In addition, Lomustine has shown the effect function in treatment of meningeal leukemia in the mouse and in children who have acute leukemia with central nervous system involvement [1].

环氧柏木烷  13567-39-0  1-Boc-吡咯-2-硼酸  135884-31-0

beta-托品醇  135-97-7  3-氰基-2,6-二氯-4-(三氟甲基)吡啶  13600-42-5

3-氰基-4-三氟甲基吡啶  13600-43-6  1,1-双(甲硫基)-2-亚硝基乙烯  13623-94-4

2-[[(2'-氰基联苯-4-基)甲基]氨基]-3-硝基苯甲酸乙酯  136285-67-1  盐酸度洛西汀  136434-34-9

1-溴-2-氟-4-碘苯  136434-77-0  4?

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>98.50%

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