性能参数

产品名称

Thioguanine

规格

50mg 500mg

货号

GOY-Y3158

 含量

>98.00%

CAS

154-42-7

别名

化学名

2-amino-3,7-dihydropurine-6-thione

分子式

C5H5N5S

分子量

分子量 167.19

溶解度

≥ 8.35 mg/mL in DMSO with gentle warming

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

6-Thioguanine (Thioguanine; 2-Amino-6-purinethiol) is an anti-leukemia and immunosuppressant agent, acts as an inhibitor of SARS and MERS coronavirus papain-like proteases (PLpros) and also potently inhibits USP2 activity, with IC50s of 25 μM and 40 μM for Plpros and recombinant human USP2, respectively.

6-Thioguanine (Thioguanine; 2-Amino-6-purinethiol) is an anti-leukemia and immunosuppressant agent, acts as an inhibitor of SARS and MERS coronavirus papain-like proteases (PLpros) and also potently inhibits USP2 activity, with IC50s of 25 μM and 40 μM for Plpros and recombinant human USP2, respectively[1]. 6-Thioguanine (Thioguanine) affects the methylation of cytosine residues by purified DNA methyltransferases including human DNMT1 and bacterial HpaII methylase. 6-Thioguanine (Thioguanine) (1 or 3 μM) decreases global cytosine methylation in Jurkat T cells and cytosine methylation in human cells at 3 μM[2]. 6-Thioguanine (Thioguanine) (18.75, 37.50, or 75.00 μM) adversely affects cell viability, but with no effect on LDH or ALT activity[3].

3-苯基-L-脯氨酸  118758-48-8  5-氯-2-硝基三氟甲苯  118-83-2

2-氯苯甲酸  118-91-2  4-氯-3,5-二硝基苯甲酸  118-97-8

二异丁基氢化铝  1191-15-7  DDTT  1192027-04-5

二氯-1,2-二硫环戊烯酮  1192-52-5  N-甲基-2-吡咯甲醛  1192-58-1

3-甲基-2-环己烯-1-酮    盐酸达波西汀  119356-77-3

2-吡咯甲酸甲酯  1193-62-0  3-奎宁环酮盐酸盐  1193-6?

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