性能参数

产品名称

Ritonavir

规格

10mM (in 1mL DMSO) 10mg 25mg 50mg 100mg

货号

GOY-Y3043

 含量

>98.00%

CAS

155213-67-5

别名

Abbott 84538, ABT-538,Ritonavir

化学名

1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[[(2S)-3-methyl-2-[[methyl-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]carbamoyl]amino]butanoyl]amino]-1,6-diphenylhexan-2-yl]carbamate

分子式

C37H48N6O5S2

分子量

分子量 720.9

溶解度

≥ 26mg/mL in DMSO with gentle warming

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Ritonavir, previously known as ABT-538, is a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) protease that exhibits potent in vitro inhibition against HIV-1 strain as well as HIV-2 strain with 50% effective concentration EC50 values of 0.022 μM and 0.16 μM respectively. Ritonavir binds to the HIV-1 protease inactivating its function to cleave the Gag and Gag-Pol polyproteins into the core proteins and viral enzymes, which results in the formation of noninfectious viral particles. X-ray crystallographic analysis reveals a hydrophobic cluster between the isopropyl substituent on the P3 thiazolyl group of ritonavir and the side chains of Pro-81 and Val-82 of HIV-1 protease within the complex of ritonavir/HIV-1 protease.

橄榄油 药用级，Ph Eur  碳化硅 ≥99.00

聚氧乙烯  average Mv 100,000, powder  纳米碳化硅 99.9% metals basis,40nm

聚氧乙烯  average Mv ~300,000, powder  二氧化锡 AR,99.5%

聚氧乙烯  average Mv ~600,000, powder  二氧化锡  ≥99.95% metals basis

聚氧乙烯  average Mv ~900,000, powder  纳米二氧化锡  99.9% meta

Ru-325141mg 5mg 10mg 20mg>98.00%Cas No. 90807-98-0C18H17N3O2

RPR1046321mg 5mg 10mg 20mg>98.00%Cas No. 154106-92-0C15H11BrCl2N2O4S

Sematilide (hydrochloride)5mg 10mg 25mg 50mg>98.00%Cas No. 101526-62-9C14H23N3O3S.HCl

SEA040010mM (in 1mL DMSO) 5mg 10mg 50mg>98.00%Cas No. 223104-29-8C21H19F2NO3

SDZ 220-581 Ammonium salt10mg 50mg 100mg 200mg>98.00%Cas No. 179411-94-0C16H20ClN2O5P

SCH 280801mg 5mg 10mg 50mg>98.00%Cas No. 76081-98-6C17H15N3O

SAR73345mg 10mg 50mg 100mg>98.00%Cas No. 1333210-07-3C21H22ClN3O