性能参数

产品名称

Minodronic acid

规格

10mg 50mg 100mg 200mg 500mg

货号

GOY-Y2994

 含量

>98.00%

CAS

180064-38-4

别名

N/A

化学名

N/A

分子式

C9H12N2O7P2

分子量

分子量 322.15

溶解度

H2O: 5 mg/mL (15.52 mM and warming); DMSO: < 1 mg/mL (insoluble or slightly soluble)

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Minodronic acid (YM-529) is a third-generation bisphosphonate that directly and indirectly prevents proliferation, induces apoptosis, and inhibits metastasis of various types of cancer cells. Minodronic acid (YM-529) is an antagonist of purinergic P2X2/3 receptors involved in pain[1][2]. P2X2/3[2]

[1]. Sato K, et al. A third-generation bisphosphonate, minodronic acid (YM529), successfully prevented the growth of bladder cancer in vitro and in vivo. Br J Cancer. 2006 Nov 20;95(10):1354-61. [2]. Tanaka M, et al. Minodronic acid induces morphological changes in osteoclasts at bone resorption sites and reaches a level required for antagonism of purinergic P2X2/3 receptors. J Bone Miner Metab. 2018 Jan;36(1):54-63.

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