性能参数

产品名称

SAFit1

规格

5mg 10mg 25mg 50mg

货号

GOY-Y2931

 含量

>98.00%

CAS

1643125-32-9

别名

N/A

化学名

N/A

分子式

C42H53NO11

分子量

分子量 747.87

溶解度

Methanol : 125 mg/mL (167.14 mM);DMSO : 62.5 mg/mL (83.57 mM);H2O : < 0.1 mg/mL (insoluble)

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

SAFit1 is a FK506 binding protein 51 (FKBP51)-specific inhibitor with a Ki of 4±0.3 nM[1][2].

SAFit1 (1-1000 nM) potently stimulates neurite outgrowth in two neuronal cell lines (N2a and SH-SY5Y) as well as in primary hippocampal neurons. SAFit1 is active over a wide concentration range[1].

[1]. Gaali S, et al. Selective inhibitors of the FK506-binding protein 51 by induced fit. Nat Chem Biol. 2015 Jan;11(1):33-7. [2]. Sidibeh CO, et al. FKBP5 expression in human adipose tissue: potential role in glucose and lipid metabolism, adipogenesis and type 2 diabetes. Endocrine. 2018 Oct;62(1):116-128.

薰衣草油 natural  3-甲氧基苯乙酮 98%

丁香酚甲醚 98%  干冰,块状,146*88*20

丁香酚甲醚 ≥98%,FCC  4,4'-二氨基二苯醚 98%

异丁香酚甲醚 99%  2,2-双[4-(4-氨基苯氧基苯)]六氟丙烷 97%

异丁香酚甲醚 ≥98%,FCC  3,4'-二氨基二苯基醚 97%

5-甲基-2,3-己二酮 94%  对酸叔丁酯 98%

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JTV-519 free base5mg 10mg 50mg>98.00%Cas No. 145903-06-6C25H32N2O2S

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