性能参数

产品名称

p53 tumor suppressor fragment

规格

1mg 5mg 10mg 25mg

货号

GOY-Y2904

 含量

>98.00%

CAS

N/A

别名

H2N-Lys-Tyr-Met-Cys-Asn-Ser-Ser-Cys-Met-OH

化学名

N/A

分子式

C41H67N11O14S4

分子量

分子量 1066.3

溶解度

≥ 53.3mg/mL in DMSO

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

p53 tumor suppressor fragment (232-240),(C41H67N11O14S4), a peptide with the sequence H2N-Lys-Tyr-Met-Cys-Asn-Ser-Ser-Cys-Met-OH, MW= 1066.3. p53 (also known as protein 53 or tumor protein 53), is a tumor suppressor protein that in humans is encoded by the TP53 gene1. p53 is crucial in multicellular organisms, where it regulates the cell cycle and, thus, functions as a tumor suppressor that is involved in preventing cancer. As such, p53 has been described as "the guardian of the genome" because of its role in conserving stability by preventing genome mutation2. p53 has many mechanisms of anticancer function, and plays a role in apoptosis, genomic stability, and inhibition of angiogenesis. In its anti-cancer role, p53 works through several mechanisms:It can activate DNA repair proteins when DNA has sustained damage. It can induce growth arrest by holding the cell cycle at the G1/S regulation point on DNA damage recognition.It can initiate apoptosis, the programmed cell death, if DNA damage proves to be irreparable3.

氢溴酸 ACS,48%  间-四苯基卟吩 97%

氢溴酸 48 wt. % in H2O, ≥99.99%  1,3-双(二苯基膦丙烷)二氯化镍 99%

2-甲基-4-甲氧基-二苯胺  98%  三氟甲磺酸镍(II) 96%

磺胺甲噁唑 98%  双[(2-二苯膦基)苯基]醚 98%

磺胺甲噁唑 分析标准品,99%  (2R,3R)-(-)-1,4-双(二苯基膦基)-2,3-O-异亚丙基-2,3-丁二醇 98%

丁香醛 98%  (2S,3S)-(+)-1,4-双(二苯基膦基)-2,3-O-异亚丙基-2,?

L-AP510mg 50mg>98.00%Cas No. 79055-67-7C5H12NO5P

L-838,41710mg 50mg>98.00%Cas No. 286456-42-6C19H19F2N7O

L-701,32410mg 50mg>98.00%Cas No. 142326-59-8C21H14ClNO3

L-701,25210mg 50mg>98.00%Cas No. 151057-13-5C13H10ClNO3

L-689,56010mg 50mg>98.00%Cas No. 139051-78-8C17H15Cl2N3O3

Licarbazepine10mg 50mg>98.00%Cas No. 29331-92-8C15H14N2O2

Levobupivacaine HCl10mM (in 1mL DMSO) 50mg>98.00%Cas No. 27262-48-2C18H28N2O.HCl