性能参数

产品名称

Rottlerin

规格

10mM (in 1mL DMSO) 10mg 50mg

货号

GOY-Y2816

 含量

>98.00%

CAS

1982/8/6

别名

N/A

化学名

(Z)-1-(6-(3-acetyl-2,4,6-trihydroxy-5-methylbenzyl)-5,7-dihydroxy-2,2-dimethyl-2H-chromen-8-yl)-3-phenylprop-2-en-1-one

分子式

C30H28O8

分子量

分子量 516.55

溶解度

100mM in DMSO

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Rottlerin was originally identified as an inhibitor of PKCδ (IC50 = 3 μM), but can also inhibit CAM kinase III and a wide range of protein kinases, including PRAK and MAPKAP-K2 (IC50s = 1.9 and 5 μM, respectively).[1],[2] It can act as a direct mitochondrial uncoupler, and stimulates autophagy by targeting a signaling cascade upstream of mTORC1.[3] Rottlerin has also been shown to have neuroprotective effects in an MPTP animal model of Parkinson’s disease.[4]

2'-羟基苯乙酮 99%  氧化铝 99．99%，镀膜

对羟基苯丙酮  98%  氧化铝G TLC专用

甲硫醚 99%  磷酸二氢铵 CP，98.5%

2-三氟甲氧基苯胺 98%  磷酸氢二铵 CP,98.0%

4-三氟甲氧基苯胺 99%  氟化钡  99.9% metals basis

DL-精氨酸盐酸盐 98%  氟化钡 AR,99.0%

Aminopeptidase N Inhibitor1mg 5mg 10mg>95.00%Cas No. 596108-59-7C17H10N2O8

Cdk2 Inhibitor II500μg 1mg 5mg>95.00%Cas No. 222035-13-4C14H11BrN4O3S

Cho-Arg (trifluoroacetate salt)1mg 5mg 10mg>95.00%Cas No. 1609010-56-1C39H71N5O3?2CF3COO

D-myo-Inositol-1,3,4,6-tetraphosphate (ammonium salt)100μg 500μg 1mg>95.00%Cas No. 142507-74-2C6H12O18P4?4NH4

Cytochalasin D1mg 5mg 10mg>95.00%Cas No. 22144-77-0C30H37NO6

Dnp-PLALWAR (trifluoroacetate salt)250μg 500μg 1mg>95.00%Cas No. N/AC46H65N13O12?XCF3COOH

Dios-Arg (trifluoroacetate salt)1mg 5mg 10mg>95.00%Cas No. 1807353-31-6C39H67N5O5?2CF3COO