性能参数

产品名称

Raddeanin A

规格

5mg 10mg 20mg

货号

GOY-Y2801

 含量

>98.00%

CAS

89412-79-3

别名

N/A

化学名

N/A

分子式

C47H76O16

分子量

分子量 897.11

溶解度

100mg/mL(111.47 mM) in DMSO

储存条件

4°C, protect from light

General tips

用途

仅供科研

价格

电询

详细内容

Raddeanin A is a natural triterpenoid saponin component of Anemone raddeana, with anti-cancer activities. Raddeanin A exerts anticancer effect on human osteosarcoma via the ROS/JNK and NF-κB signal pathway[1][2][3][4].

[1]. Ma B, et al. Raddeanin A, a natural triterpenoid saponin compound, exerts anticancer effect on human osteosarcoma via the ROS/JNK and NF-κB signal pathway. Toxicol Appl Pharmacol. 2018 Aug 15;353:87-101. [2]. Guo SS, et al. Raddeanin A promotes apoptosis and ameliorates 5-fluorouracil resistance in cholangiocarcinoma cells. 3.411World J Gastroenterol. 2019 Jul 14;25(26):3380-3391. [3]. Xia H, et al. Raddeanin A down-regulates androgen receptor and its splice variants in prostate cancer. J Cell Mol Med. 2019 May;23(5):3656-3664. [4]. Meng C, et al. Raddeanin A Induces Apoptosis and Cycle Arrest in Human HCT116 Cells through PI3K/AKT Pathway Regulation In Vitro and In Vivo. Evid Based Complement Alternat Med. 2019 May 26;2019:7457105.

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