性能参数

产品名称

Mcl1-IN-8

规格

5mg 10mg 50mg

货号

GOY-Y2745

 含量

>98.00%

CAS

678158-55-9

别名

N/A

化学名

N/A

分子式

C22H23N3O2S

分子量

分子量 393.5

溶解度

DMSO: 50 mg/mL (127.06 mM)

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Mcl1-IN-8 (Comp8) is a Mcl-1-PUMA interface inhibitor, with a Ki of 0.3 μM. Mcl1-IN-8 (Comp8) exhibits dual activity on reduce PUMA-dependent apoptosis while deactivating Mcl-1-mediated anti-apoptosis in cancer cells[1].

[1]. Liu J, et al. Targeting the apoptotic Mcl-1-PUMA interface with a dual-acting compound. Oncotarget. 2017 Apr 20;8(33):54236-54242.

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