性能参数

产品名称

Mcl1-IN-9

规格

100mg 250mg 500mg

货号

GOY-Y2744

 含量

>98.00%

CAS

1810769-31-3

别名

N/A

化学名

N/A

分子式

C37H39ClN4O4

分子量

分子量 639.18

溶解度

Soluble in DMSO

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Mcl1-IN-9 is a potent myeloid cell leukemia-1 (Mcl-1) Inhibitor with an IC50 of 446 nM in reengineered BCR-ABL+ B-ALL cells and a Ki of 0.03 nM[1]. Mcl-1|0.03 nM (Ki)

Mcl1-IN-9 inhibits growth of Mcl-1 dependent tumor cell lines in the nanomolar range[1].

Mcl1-IN-9 inhibits the growth of hematological and triple negative breast cancer xenografts at well tolerated doses[1].

[1]. Lee T, et al, Discovery of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors That Demonstrate in Vivo Activity in Mouse Xenograft Models of Human Cancer. J Med Chem. 2019 Apr 25;62(8):3971-3988.

二乙基二硫代氨基甲酸钠(铜试剂) ACS，≥99.0%，用于测定和分离  汞标准溶液100μg/ml,基体:3%硝酸

硅酸 AR  汞标准溶液10.0ng/g，基体: 0.4mol/L HCL，K+2.2mg/L，Na+23mg/L

升华硫 AR,99.5%  钼标准溶液 1000μg/ml

升华硫 CP,99.0%  钼标准溶液 500 mg/L,溶剂:微量硫酸

升华硫 99.99% metals basis,薄片  钼标准溶液 100μg/mL，基体: 1%HCl

无水磷酸二氢钠 用于分子?

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