性能参数

产品名称

Linderalactone

规格

1mg 5mg 10mg

货号

GOY-Y2735

 含量

>98.00%

CAS

728-61-0

别名

N/A

化学名

N/A

分子式

C15H16O3

分子量

分子量 244.29

溶解度

DMSO: 50 mg/mL (204.67 mM)

储存条件

-20°C, protect from light

General tips

用途

仅供科研

价格

电询

详细内容

Linderalactone is an important sesquiterpene lactone isolated from Radix linderae. Linderalactone inhibits cancer growth by modulating the expression of apoptosis-related proteins and inhibition of JAK/STAT signalling pathway. Linderalactone also inhibits the proliferation of the lung cancer A-549 cells with an IC50 of 15 μM[1][2].

Linderalactone (0-100 μM; 24 hours; A549 cells) treatment inhibits the growth of A549 cells concentration-dependently. The IC50 of linderalactone is 15 μM[1].Linderalactone (7.5-30 μM; A549 cells) treatment induces apoptosis in A549 cells in a dose-dependent manner[1].Linderalactone (7.5-30 μM; 24 hours; A549 cells) treatment induces G2/M cell cycle arrest of A549 cells dose-dependently[1].Linderalactone (7.5-30 μM; A549 cells) inhibits the expression of STAT1, JAK1 and JAK2. Linderalactone could also inhibit the phosphorylation of pSTAT1, pSTAT-2, pJAK1 and pJAk2[1]. Cell Viability Assay[1] Cell Line: Lung cancer A549 cells

[1]. Deng Y, et al. Linderalactone inhibits human lung cancer growth by modulating the expression of apoptosis-related proteins, G2/M cell cycle arrest and inhibition of JAK/STAT signalling pathway. J BUON. 2019 Mar-Apr;24(2):566-571. [2]. Qinghua Sun, et al. Preparative Isolation and Purification of Linderalactone and Lindenenol from Radix linderae by HSCCC. Journal of Liquid Chromatography & Related Technologies. Aug 2005:113-121.

铬酸钾 CP  氯离子(Cl-)标准溶液 100μg/mL，基体:水

铬酸钾 GR  铈标准溶液 1000μg/ml

铬酸钾 PT  铈标准溶液 1000μg/ml，基体：10%HNO3

铬酸钾 SP  色度标准溶液 500度

铬酸钾 99.99% metals basis  化学耗氧量（COD）-铬法标准溶液 1000μg/ml

铬酸钾 ACS  氰化物标准溶液 1.000 g/L in H2O

Relebactam1mg 5mg 10mg 25mg 50mg>98.00%Cas No. 1174018-99-5C12H20N4O6S

RIG-1 modulator 110mM*1mLinDMSO 1mg 5mg 10mg 50mg>98.00%Cas No. 1428729-63-8C14H17N5OS2

Ribocil-C10mM*1mLinDMSO 5mg 10mg 50mg 100mg>98.00%Cas No. 1825355-56-3C21H21N7OS

Ribocil B (Ribocil S enantiomer)2mg 5mg 10mg 50mg 100mg>98.00%Cas No. 1825355-55-2C19H22N6OS

RO-91875mg 10mM*1mL in Water 50mg 100mg 200mg>98.00%Cas No. 876708-03-1C9H12N6O5