性能参数

产品名称

Larotaxel

规格

1mg 5mg 10mg

货号

GOY-Y2734

 含量

>98.00%

CAS

156294-36-9

别名

N/A

化学名

N/A

分子式

C45H53NO14

分子量

分子量 831.9

溶解度

DMSO: ≥ 50 mg/mL (60.10 mM)

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Larotaxel (XRP9881) is a taxane analogue with preclinical activity against taxane-resistant breast cancer. Larotaxel (XRP9881) exerts its cytotoxic effect by promoting tubulin assembly and stabilizing microtubules, ultimately leading to cell death by apoptosis. It presents the ability to cross the blood brain barrier and has a much lower affinity for P-glycoprotein 1 than Docetaxel[1][2][3].

[1]. Diéras V, et al. Phase II multicenter study of larotaxel (XRP9881), a novel taxoid, in patients with metastatic breast cancer who previously received taxane-based therapy. Ann Oncol. 2008 Jul;19(7):1255-60. [2]. Morris PG, et al. Novel anti-tubulin cytotoxic agents for breast cancer. Expert Rev Anticancer Ther. 2009 Feb;9(2):175-85. [3]. Zatloukal P, et al. Randomized multicenter phase II study of larotaxel (XRP9881) in combination with cisplatin or gemcitabine as first-line chemotherapy in nonirradiable stage IIIB or stage IV non-small cell lung cancer. J Thorac Oncol. 2008 Aug;3(8):894-901.

溴化钾 FT-IR grade, ≥99.5%  钴标准溶液100?g/ml，基体: 1%硝酸

溴化钾 99.997% metals basis  铯标准溶液 1000μg/ml

溴化钾 分析标准品，99.94%  六价铬标准溶液 六价铬标准溶液 1000μg/ml

氟化钾，无水 GR，粉末  氯离子标准溶液1000μg/ml

氟化钾，无水 99.9% metals basis  氯离子标准溶液500mg/L，溶剂：水

铬酸钾 AR  氯离子(Cl-)标准溶液 1000μg/mL，基体:水

Q2031mg 5mg 10mg 50mg 100mg>98.00%Cas No. 1334719-95-7C29H28ClF3N4O2

Pyrithione5mg 10mg 25mg 50mg 100mg>98.00%Cas No. 1121-30-8C5H5NOS

Pyrantel Pamoate10mM (in 1mL DMSO) 10mg 25mg 50mg 100mg>98.00%Cas No. 22204-24-6C23H16O6.C11H14N2S

Retro-210mM 1 mL in DMSO 5mg 10mg 50mg 100mg>98.00%Cas No. 1429192-00-6C19H16N2OS

Resiquimod (R-848)10mM (in 1mL DMSO) 10mg 25 mg 50mg 100mg>98.00%Cas No. 144875-48-9C17H22N4O2

Remdesivir (GS-5734)10 mM * 1 mL in DMSO 5mg 10mg 50mg 100mg>98.00%Cas No. 1809249-37-3C27H35N6O8P