性能参数

产品名称

Tubulysin G

规格

1mg 5mg

货号

GOY-Y2721

 含量

>98.00%

CAS

799822-08-5

别名

N/A

化学名

N/A

分子式

C43H63N5O10S

分子量

分子量 842.05

溶解度

Soluble in DMSO

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

Tubulysin G is a highly cytotoxic peptide isolated from the myxobacterial species Archangium geophyra and Angiococcus disciformis. Tubulysin displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC50 values in the lower nanomolar range[1]. Tubulysin G is a cytotoxic activity tubulysin which inhibits tubulin polymerization and leads to cell cycle arrest and apoptosis[2].

[1]. Kubicek K, et al. The tubulin-bound structure of the antimitotic drug tubulysin. Angew Chem Int Ed Engl. 2010 Jun 28;49(28):4809-12. [2]. Vlahov IR, et al. Acid mediated formation of an N-acyliminium ion from tubulysins: a new methodology for the synthesis of natural tubulysins and their analogs. Bioorg Med Chem Lett. 2011 Nov 15;21(22):6778-81.

硫氰酸钾标准溶液 100g/L  邻甲基 98%

焦硫酸钾 AR,98%  α,α,α-三氯甲苯 99%

焦硫酸钾 CP,97%  肉桂腈 97%

磷酸氢二钾,无水 GR  丁位癸内酯 98%

磷酸氢二钾,无水 99.99% metals basis  丙位癸内酯 98%

邻苯二甲酸氢钾 AR，99.8%  丁位十二内酯 98%

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PPA-9041mg 5mg 10mg 20mg>98.00%Cas No. 30189-85-6C28H42BrN3S

Propargylcholine (bromide)10mg 50mg 100mg 250mg>98.00%Cas No. 111755-76-1C7H14NO.Br

Proguanil10mM*1mLinDMSO 10mg 25mg 50mg>98.00%Cas No. 500-92-5C11H16ClN5

PSI-79761mg 5mg 10mg 50mg>98.00%Cas No. 1190308-01-0C22H29FN3O9P

PSI-7409 tetrasodium1mg 5mg 10mM*1mLinWater 25mg>98.00%Cas No. 1621884-22-7C10H16FN2Na4O14P3