性能参数

产品名称

SMBA 1

规格

0 mg 50 mg

货号

GOY-Y2698

 含量

>98.00%

CAS

906440-37-7

别名

N/A

化学名

N/A

分子式

C20H13NO3

分子量

分子量 315.32

溶解度

Soluble in DMSO

储存条件

Store at -20°C

General tips

用途

仅供科研

价格

电询

详细内容

High affinity and selective activator of Bax (Ki = 43.3 nM). Binds to the S184 binding pocket to block Bax phosphorylation. Does not bind to other Bcl-2 family members, including Bcl-2, Bak and Bid. Facilitates Bax insertion into the mitochondrial membrane and promotes Bax-dependent cytochrome c release. Induces apoptosis in lung cancer cell lines expressing high levels of Bax selectively over normal cells expressing low levels of Bax. Represses tumor growth of A549 lung cancer xenografts in mice.

Xin et al (2014) Small-molecule Bax agonists for cancer therapy. Nat.Commun. 5 4935 PMID:25230299

发烟硝酸 GR  邻苯二甲酸二乙酯 AR,99.5%

发烟硝酸 AR  邻苯二甲酸二乙酯 CP,99.0%

发烟硝酸 ACS reagent, ≥90.0%  邻苯二甲酸二乙酯 分析标准品

氮川三乙酸 AR，98.5%  三乙酸甘油酯 AR,98.5%

氮川三乙酸 CP  戊硫醇 Standard for GC, ≥99.5% (GC)

氮川三乙酸 ACS, ≥99.0%  戊硫醇 98%

Tylosin (Tylosin A)10mM*1mLinDMSO 50mg>98.00%Cas No. 1401-69-0C46H77NO17

Vanillic acid100mg 500mg>98.00%Cas No. 121-34-6C8H8O4

Valnemulin HCl10mM (in 1mL DMSO) 50mg>98.00%Cas No. 133868-46-9C31H52N2O5S.HCl

Validamycin A500mg 1g>98.00%Cas No. 37248-47-8C20H35NO13

Valganciclovir50mg 100mg>98.00%Cas No. 175865-60-8C14H22N6O5

Virginiamycin S15mg 25mg>98.00%Cas No. 23152-29-6C43H49N7O10

Virginiamycin M15mg 25mg>98.00%Cas No. 21411-53-0C28H35N3O7