(-)-Caryophyllene oxide
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产品名称:
(-)-Caryophyllene oxide
产品型号:
GOY-Y0014
产品展商:
谷研
产品文档:
无相关文档
发布时间:2023-04-07
简单介绍
(-)-Caryophyllene oxideDMF: 20 mg/ml,DMSO: 10 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
(-)-Caryophyllene oxide
的详细介绍
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性能参数
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产品名称
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(-)-Caryophyllene oxide
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规格
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100mg 1g
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货号
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GOY-Y0014
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含量
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>98.00%
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CAS
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1139-30-6
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别名
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N/A
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化学名
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N/A
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分子式
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C15H24O
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分子量
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分子 220.4
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溶解度
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DMF: 20 mg/ml,DMSO: 10 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
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储存条件
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Store at -20°C
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General tips
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For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
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用途
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仅供科研
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价格
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电询
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详细内容
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(-)-Caryophyllene oxide is a bicyclic sesquiterpene and a metabolite of β-caryophyllene that has been found in C. sativa and has anticancer properties. Unlike β-caryophyllene, (-)-caryophyllene oxide does not bind to the cannabinoid (CB) receptor CB2 (Ki = >20 μM). It induces calcium currents in HL-60 cells expressing CB2 receptors but also does so in CB2-deficient cells. (-)-Caryophyllene oxide is cytotoxic to HepG2, AGS, HeLa, SNU-1 and SNU-16 cells (IC50s = 3.95, 12.6, 13.55, 16.79, and 27.39 μM, respectively). It is the volatile component of C. sativa sensed by narcotic detection dogs. Formulations containing (-)-caryophyllene have been used as flavoring agents.
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